![]() These conditions increase your risk of getting blood clots, especially if you are using an estrogen product. Tell your doctor if you just had or will be having surgery, or if you will be confined to a chair or bed for a long time (such as a long plane flight). Estrogens combined with smoking further increases your risk of stroke, blood clots, high blood pressure, and heart attack, especially in women older than 35. mental/mood disorders (such as dementia, depression)ĭo not smoke or use tobacco.uterus problems (such as fibroids, endometriosis).a certain hormone problem (hypoparathyroidism).mineral imbalance (low or high level of calcium in the blood). ![]() blood clotting disorders (such as protein C or protein S deficiency).family or personal history of a certain swelling disorder (angioedema).family medical history (especially breast lumps, cancer, blood clots).certain cancers (such as breast cancer, cancer of the uterus/ovaries).Talk to your pharmacist for more details.īefore using this medication, tell your doctor or pharmacist your medical history, especially of: This product may contain inactive ingredients, which can cause allergic reactions or other problems. You may report side effects to Health Canada at 1-86.īefore using estradiol, tell your doctor or pharmacist if you are allergic to it or if you have any other allergies. You may report side effects to FDA at 1-80 or at In Canada - Call your doctor for medical advice about side effects. If you notice other effects not listed above, contact your doctor or pharmacist.Ĭall your doctor for medical advice about side effects. This is not a complete list of possible side effects. itching/swelling (especially of the face/tongue/throat).However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: tingling/weakness/numbness in the arms/legsĪ very serious allergic reaction to this product is rare.sudden vision changes (such as partial/complete blindness).Get medical help right away if you have any serious side effects, including: This medication may rarely cause serious problems from blood clots (such as heart attacks, strokes, deep vein thrombosis, pulmonary embolism). increased or new vaginal irritation/itching/odor/discharge.unusual vaginal bleeding (such as spotting, breakthrough bleeding, prolonged/recurrent bleeding).mental/mood changes (such as depression, memory loss).Tell your doctor right away if you have any serious side effects, including: Many people using this medication do not have serious side effects. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Nausea/vomiting, bloating, diarrhea, breast tenderness, headache, or weight changes may occur. If you will be taking this medication long-term, you should have regular complete physical exams (for example, once a year) as directed by your doctor. Discuss the use of this medication with your doctor and check with him/her regularly (for example, every 3 to 6 months) to see if you still need to take this medication. This medication should be used at the lowest effective dose and for the shortest amount of time. The risk for serious side effects may depend on the dose of estrogen and the length of time it is used. Estrogen, when used with a progestin, can increase the risk of heart disease (such as heart attacks), stroke, serious blood clots in the lungs/legs, dementia, and cancer of the breast/ovaries. Estrogens alone do not appear to increase the risk of breast cancer when used for up to 7 years. In postmenopausal women, estrogens can increase the risk of cancer of the ovaries, stroke, dementia, and serious blood clots in the legs. Tell your doctor right away if you have any unusual vaginal bleeding. Taking a progestin as directed by your doctor can help decrease this risk. Estrogens should not be used to prevent heart disease or dementia.Įstrogens can increase the risk of cancer of the uterus (endometrial cancer). Discuss the risks and benefits of hormone treatment with your doctor. Estrogens, either used alone or with another hormone (progestin), have rarely caused very serious side effects.
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